womens microbiome

Candidiasis and the Vaginal Microbiome: Where Probiotics Can Help

it’s Emily here.

Vulvovaginal candidiasis is one of the most common infections in women — and also one of the most often mistaken. Data from the CDC show that its symptoms — such as itching, discharge, and discomfort — can easily be confused with other causes of vaginitis, making a clinical diagnosis essential before starting any treatment. The ACOG also points out that there are “uncomplicated” forms, usually sporadic and easily resolved, but also “complicated” cases, such as recurrent infections associated with diabetes, pregnancy, or immunosuppression, which require specific approaches.

Ignoring proper care carries risks: the inappropriate use of antifungals can encourage resistance in species such as Candida glabrata; symptoms may persist; and the impact on quality of life can be significant. In more severe situations — like invasive infections in hospitalized patients — delays in treatment can even increase mortality.

The Role of the Vaginal Microbiome

The human body has natural defenses against the excessive growth of Candida. One of the most important is the Lactobacillus flora, which helps maintain an acidic vaginal pH and produces substances such as hydrogen peroxide, making it harder for fungi to thrive. When this balance is disrupted — whether by antibiotics, hormonal changes, or weakened immunity — Candida can multiply.

Where Probiotics Come In

American medical guidelines are clear: probiotics do not replace antifungal treatment in cases of active candidiasis. Still, there is growing scientific interest in their role as support for vaginal microbiome balance:

  • Small, low-quality studies suggest that combining probiotics with antifungals may improve short-term clinical cure rates and reduce recurrences over about a month.
  • Specific strains of Lactobacillus, such as L. rhamnosus GR-1 and L. reuteri RC-14, have shown in research the ability to recolonize the vaginal flora and compete with Candida, helping to restore the natural environment.
  • Reviews (such as Cochrane’s) emphasize that evidence is still preliminary but biologically plausible, encouraging further research.

What This Means for You

For women, the practical message is simple:

  • If you experience symptoms of candidiasis, consult a healthcare professional. Diagnosis is important, and antifungal therapy is the foundation of treatment.
  • Probiotics can be allies in maintaining vaginal balance, helping to support the microbiome and reduce the factors that favor recurrence.
  • Ongoing use can be part of a preventive wellness strategy — but it should never replace medical care when needed.


Caring for candidiasis isn’t just about treating symptoms — it’s about looking at the vaginal ecosystem as a whole. Probiotics are not medicines for fungal infections, but they can be part of an intimate care routine that values balance, prevention, and quality of life.

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